Trends in Vaccine Development


Vaccines to protect against infectious disease are the single most effective medical product, but developing new ones is a challenging and lengthy process, limiting their use in developing countries where they are most needed. Once a new vaccine is developed, it undergoes animal testing, which is time-consuming and does not necessarily reflect human immunity.

A variety of new strategies are emerging to facilitate vaccine development and delivery:

1 Modular approaches to vaccine production

Simulating immune systems

3 Boosting efficacy with adjuvants

4 New vaccine delivery systems

5 Increasing vaccine stability

6 Understanding pathogenesis

“It can take decades from the start of vaccine development to FDA approval at huge cost,” says Ofer Levy, MD, PhD, a physician and researcher in the Division of Infectious Diseases at Boston Children’s Hospital. “We are working on making the process faster and more affordable.”